TriangleBiopsy Procedure (NCT03907475)
Biopsy Procedure trial for Locally Advanced Malignant Solid Neoplasm (NCT03907475). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with inoperable locally advanced or metastatic solid tumors after standard treatment fails, or when no survival-prolonging standard option exists. Prior-treatment exceptions apply.
The idea: durvalumab blocks PD-L1 to support immune attack. Separate groups receive it alone or with gemcitabine, liposomal doxorubicin, capecitabine, carboplatin, paclitaxel or nab-paclitaxel. Cancer type and prior immunotherapy restrict the durvalumab-only group. Biopsies help study immune changes.
This phase 2 study plans 115 patients. A P Chen leads the National Cancer Institute study in Bethesda, the sole recruiting US site. Safety is the primary goal.
Public record; not medical advice.
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