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Yttrium-90 Radiation Segmentectomy… (NCT07586046)

Defining the Ablative Dose for Y-90 TARE: a one-minute explainerNCT075860461 min

Yttrium-90 Radiation Segmentectomy (Y90 RS) using glass microspheres trial for HCC - Hepatocellular Carcinoma (NCT07586046). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with hepatocellular carcinoma, cholangiocarcinoma or liver metastases unsuitable for surgery or standard ablation. Disease outside the liver is excluded; treatment must cover no more than two liver segments.

The idea: radioactive yttrium-90 glass beads enter vessels feeding the tumor to deliver radiation locally. Separate groups with and without cirrhosis receive escalating doses. PET and MRI scans assess radiation distribution and tissue destruction while researchers monitor safety.

This phase 2 study plans 30 patients. Northwestern University sponsors it in Chicago, the single recruiting US site.

Public record; not medical advice.

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