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Biopsy Procedure (NCT06940297)

Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma: a one-minute explainerNCT069402971 min

Biopsy Procedure trial for Recurrent Multiple Myeloma (NCT06940297). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with relapsed or refractory multiple myeloma after at least three treatment lines, including a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 antibody. Ciltacabtagene autoleucel must be available.

The idea: Genetically modified T cells target cancer. Oral dasatinib and quercetin are added in courses before and after the infusion, with cyclophosphamide and fludarabine beforehand. Researchers measure undetectable residual disease at three months with required marrow samples and PET imaging.

This phase 2 study plans 44 patients. Yi Lin leads at Mayo Clinic, Rochester, the sole recruiting US site.

Public record; not medical advice.

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