TriangleRadical cystectomy (NCT07048457)
Radical cystectomy trial for Locally Advanced Urothelial Carcinoma (NCT07048457). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with locally advanced or limited metastatic urothelial cancer, with no more than five metastatic lesions at diagnosis. Disease must be stable or responding after first-line enfortumab-vedotin-based therapy, started at least three months before surgery.
The idea: remove the bladder and pelvic lymph nodes, create urinary diversion, and remove eligible metastatic lesions. Prior radiation to metastases is allowed. This tests whether surgery can consolidate disease control after systemic treatment; researchers measure one-year progression-free survival.
This phase 2 study plans 32 patients. Fed Ghali leads Yale’s New Haven site.
Public record; not medical advice.
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