TriangleBiopsy Procedure (NCT05886036)
Biopsy Procedure trial for Nodular Lymphocyte Predominant B-Cell Lymphoma (NCT05886036). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with nodular lymphocyte-predominant Hodgkin lymphoma needing treatment: untreated stages IB–IV, or previously treated disease at any stage. Active transformation and relapse within six months of rituximab are excluded.
The idea: compare two CD20-directed antibodies. Mosunetuzumab also links lymphoma cells to T-cells. Patients are randomized to mosunetuzumab injections or rituximab, initially infused, with later injections or infusions. Researchers measure time without progression. Progression may permit crossover at week twelve. Baseline tissue and bone-marrow biopsies are required.
This phase 2 study plans 70 patients. NCI sponsors 33 recruiting US sites.
Public record; not medical advice.
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