TriangleCisplatin (NCT07475286)
Cisplatin trial for Synchronous Gastric Peritoneal Carcinomatosis (NCT07475286). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with gastric or Siewert-3 junction adenocarcinoma and peritoneal spread after 4–6 months of systemic therapy, without progression elsewhere. Biomarker exclusions include MSI-H/dMMR, TMB>30, CPS>40, POLE mutations, claudin-18.2 positivity, BRAF V600E, RET fusions and HER2 positivity.
The idea: add heated cisplatin and mitomycin inside the abdomen to disrupt cancer-cell replication. Up to three laparoscopic treatments replace scheduled systemic treatments every six weeks.
This phase 2 study plans 22 patients. Haroon Choudry leads at UPMC Hillman in Pittsburgh, the sole recruiting US site.
Public record; not medical advice.
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