TrianglePaclitaxel (NCT06441890)
Paclitaxel trial for Breast Cancer (NCT06441890). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with untreated, nonmetastatic HER2-positive breast cancer, stage cT1c–T3 and cN0–N2, whose gene-expression test also shows the HER2-enriched subtype. Preoperative chemotherapy and surgery must be planned.
The idea: trastuzumab and pertuzumab target HER2 through different binding sites. They accompany one taxane chosen by the doctor: paclitaxel, nab-paclitaxel, or docetaxel. Researchers test whether this biomarker-selected treatment leaves no invasive cancer in the breast or sampled lymph nodes at surgery.
This phase 2 study plans 28 patients. The University of Illinois Chicago sponsors the sole recruiting US site.
Public record; not medical advice.
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