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Reproductive organ sparing radical… (NCT06184516)

Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical Cystectomy: a one-minute explainerNCT061845161 min

Reproductive organ sparing radical cystectomy trial for Urothelial Carcinoma Bladder (NCT06184516). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for women aged 18 to 99 with bladder urothelial cancer who can undergo radical cystectomy. Regional/distant metastases are excluded. A specified reproductive organ must remain; inherited BRCA1 or BRCA2 mutations are excluded.

The idea: use a decision tool to select patients for reproductive-organ preservation during bladder removal. Favorable findings lead to organ-sparing surgery; unfavorable findings lead to conventional surgery. MRI and cystoscopy are required. Researchers check margins for remaining cancer.

This phase 2 study plans 127 patients. University of Florida leads it in Gainesville, the sole recruiting US site.

Public record; not medical advice.

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