Trianglealpha beta depletion (NCT04099966)
alpha beta depletion trial for Acute Leukemia (NCT04099966). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for patients aged one day to 30 years with qualifying acute leukemia, high-risk myelodysplastic syndrome, lymphoma or specified non-cancer blood diseases who need donor stem-cell transplantation.
The idea: remove alpha-beta T cells and CD19-positive B cells from the donated cells before transplantation. Patients receive preparatory treatment selected for their disease and health. Researchers track adverse effects, engraftment, immune recovery, graft-versus-host disease and quality of life.
This phase 2 study plans 20 patients. Mitchell Cairo leads at New York Medical College in Valhalla, the sole recruiting US site.
Public record; not medical advice.
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