TriangleStandard of Care Chemotherapy +… (NCT06728072)
Standard of Care Chemotherapy + Metronidazole, ciprofloxacin, aspirin trial for Colorectal Cancer (NCT06728072). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with stage IV colorectal cancer starting first-line fluorouracil-based combination chemotherapy. Measurable disease is required; adjuvant treatment is allowed if completed over six months before.
The idea: the study tests whether changing the microbiome affects treatment response. Patients are randomized to chemotherapy alone or chemotherapy with metronidazole, ciprofloxacin, and aspirin for 28 days. Aspirin may be omitted when contraindicated. The doctor selects the chemotherapy regimen. Researchers assess tumor responses and safety.
This phase 2 study plans 97 patients. Emily Kinsey leads at Virginia Commonwealth; two Richmond sites are recruiting.
Public record; not medical advice.
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