TriangleBiospecimen Collection (NCT07037004)
Biospecimen Collection trial for Clear Cell Renal Cell Carcinoma (NCT07037004). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults after removal of high-risk kidney cancer with a clear-cell or sarcomatoid component. Metastatic cancer can qualify if surgery leaves no evidence of disease. Prior systemic immunotherapy for kidney cancer is excluded.
The idea: test whether oral CBM588 bacteria change the gut microbiome and immune signaling. Random assignment adds twice-daily CBM588 to pembrolizumab or gives pembrolizumab alone. Infusions repeat every three or six weeks for up to one year. Researchers measure IL-12.
This phase 2 study plans 62 patients. Wesley Yip leads City of Hope’s Duarte and Irvine sites.
Public record; not medical advice.
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