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Biopsy Procedure (NCT06064097)

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC): a one-minute explainerNCT060640971 min

Biopsy Procedure trial for Stage II Nasopharyngeal Carcinoma AJCC v8 (NCT06064097). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for children and young adults aged 21 or younger with newly diagnosed stage II–IV nasopharyngeal carcinoma. Previous head-and-neck radiation is excluded.

The idea: nivolumab blocks PD-1 immune suppression while chemotherapy attacks cancer cells. Treatment starts with three cycles of nivolumab, gemcitabine and cisplatin. Consolidation combines nivolumab, two cisplatin cycles and response-adjusted radiation. Six monthly nivolumab cycles follow. Researchers primarily assess serious immune side effects and study disease control and radiation effects. Research biopsies and samples are optional.

This phase 2 study plans 50 patients. NCI sponsors 74 recruiting US sites.

Public record; not medical advice.

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