Telisotuzumab Adizutecan (NCT07023289)
Telisotuzumab Adizutecan trial for Colorectal Cancer (NCT07023289). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with colon or rectal adenocarcinoma, no cancer visible on scans, but positive circulating tumor DNA after surgery and qualifying chemotherapy. At least three months of platinum-doublet treatment and surgical tissue for personalized DNA testing are required.
The idea: telisotuzumab adizutecan carries a DNA-replication-blocking payload to cells bearing c-Met. The study compares this intravenous drug alone with usual care. Researchers track recurrence, survival and side effects. Positive tumor-DNA testing must meet specified timing limits after treatment.
This phase 2 study plans 140 patients. AbbVie sponsors twenty-one recruiting US sites.
Public record; not medical advice.
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