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Chemotherapy (NCT07293247)

A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment: a one-minute explainerNCT072932471 min

Chemotherapy trial for Lung Non-Small Cell Carcinoma (NCT07293247). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with non-small-cell lung cancer whose surgery shows mediastinal lymph-node involvement after preoperative systemic treatment. Complete removal, no distant spread, and no known EGFR mutation or ALK rearrangement are required.

The idea: test whether postoperative radiation adds benefit to standard chemotherapy or immunotherapy. Random assignment gives standard treatment alone or radiation first, followed by standard treatment. Beams use different intensities to target tissue while limiting exposure nearby. Researchers assess disease-free survival and heart-lung toxicity.

This phase 2 study plans 164 patients. Alliance sponsors it across 111 recruiting US sites.

Public record; not medical advice.

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