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Selinexor 60 MG (NCT04661137)

A Study of Selinexor, in Combination With Carfilzomib, Daratumumab or Pomalidomide in Patients With Multiple Myeloma: a one-minute explainerNCT046611371 min

Selinexor 60 MG trial for Multiple Myeloma (NCT04661137). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults whose multiple myeloma progresses or resists treatment with carfilzomib, pomalidomide or daratumumab.

The idea: add oral selinexor and dexamethasone to the corresponding drug. Selinexor blocks a protein that moves growth-control proteins out of the cell nucleus. Treatment is assigned by prior therapy, not randomly. Researchers measure responses; doses and schedules differ between groups.

This phase 2 study plans 96 patients. Noa Biran leads it for Hackensack Meridian Health; two US sites are recruiting, in Hackensack and Washington, D.C.

Public record; not medical advice.

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