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Ultra Low Dose 4 Gy Radiation (NCT05929612)

A Study of Response Adapted Ultra Low Dose 4 Gy Radiation for Definitive Therapy of Marginal Zone Lymphoma: a one-minute explainerNCT059296121 min

Ultra Low Dose 4 Gy Radiation trial for Lymphoma (NCT05929612). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with stage I–II marginal-zone lymphoma. Prior treatment is allowed; residual-disease requirements vary by setting. Systemic therapy must not be planned before the first post-radiation assessment; gastric MALT lymphoma requires Helicobacter pylori testing.

The idea: researchers test whether radiation can control lymphoma using less treatment. Patients receive four gray in two treatments over one–two days. Response determines whether twelve additional gray are needed. Researchers assess response, recurrence, survival, and toxicity.

This phase 2 study plans 50 patients. Jillian Gunther leads at MD Anderson, Houston, the sole recruiting US site.

Public record; not medical advice.

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