Triangle3-Dimensional Conformal Proton… (NCT06368817)
3-Dimensional Conformal Proton Radiation Therapy trial for Basal Ganglia Germinoma (NCT06368817). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for patients aged three through 29 with newly diagnosed central nervous system germinoma meeting tumor-marker and imaging criteria. Localized and metastatic disease are included.
The idea: intravenous carboplatin and etoposide attack dividing cancer cells, followed by radiation. The radiation field and dose depend on tumor location, spread, and response. Selected complete responders receive reduced ventricular radiation plus a tumor boost. Second-look surgery may guide treatment. Researchers track disease control and effects.
This phase 2 study plans 240 patients. Mohamed Abdelbaki leads for Children's Oncology Group; 95 US sites are recruiting.
Public record; not medical advice.
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