TriangleLifileucel (NCT07741877)
Lifileucel trial for Sarcoma (NCT07741877). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for people aged 16–70 with unresectable or metastatic undifferentiated pleomorphic sarcoma or dedifferentiated liposarcoma progressing after one to three systemic treatments, including an anthracycline. Older patients may enter after medical-monitor discussion.
The idea: grow tumor-recognizing immune cells from surgically removed tumor tissue, then return them as lifileucel. Patients receive cyclophosphamide and fludarabine to reduce existing lymphocytes before the infusion, followed by aldesleukin to support the cells. Measurable tumor must remain after collection.
This phase 2 study plans 80 patients. Iovance sponsors recruiting sites in Tampa and New York.
Public record; not medical advice.
Already in a trial?
It turns into a project to manage: visits, scans, labs, side effects and paperwork. Triangle keeps it organized in one place for you or for whoever's helping.
Organize my trial7-day free trial, then $9 a month. Cancel anytime.