TriangleBiopsy Procedure (NCT04322318)
Biopsy Procedure trial for Anaplastic Kidney Wilms Tumor (NCT04322318). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for patients aged 30 or younger with newly diagnosed stage II–IV diffuse anaplastic Wilms tumor, or favorable-histology Wilms tumor at first relapse after multidrug chemotherapy.
The idea: chemotherapy attacks tumor cells through different pathways. Newly diagnosed and standard-risk relapse groups receive UH-3. Higher-risk relapses receive alternating ifosfamide, carboplatin, etoposide and cyclophosphamide, topotecan. Previous drug exposure determines relapse risk. Surgery or radiation is used as indicated. Researchers measure event-free survival.
This phase 2 study plans 256 patients. James Geller leads for Children's Oncology Group; 172 US sites are recruiting.
Public record; not medical advice.
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