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Stereotactic body radiotherapy (NCT05674396)

3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial: a one-minute explainerNCT056743961 min

Stereotactic body radiotherapy trial for Head and Neck Squamous Cell Carcinoma (NCT05674396). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with head-and-neck squamous-cell cancer who cannot receive treatment intended to eliminate the disease, after review. Prior treatment and spread are allowed if radiation remains appropriate.

The idea: patients are randomized to stereotactic body radiation or traditional radiation schedules. The stereotactic approach tests delivery of a tumor dose over fewer treatments. Researchers compare local cancer control, pain, symptoms, survival, and toxicity. The study doctor determines each patient's radiation schedule.

This phase 2 study plans 108 patients. Jay Reddy leads at MD Anderson in Houston, the sole recruiting US site.

Public record; not medical advice.

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