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Decitabine + Venetoclax Maintenance (NCT06129734)

How Decitabine + Venetoclax Maintenance worksNCT061297341 min

Decitabine + Venetoclax Maintenance trial for Acute Myeloid Leukemia and Myelodysplastic Syndromes After Allogeneic Transplant (NCT06129734). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with acute myeloid leukemia or myelodysplastic syndromes who are having a donor stem cell transplant.

The idea: after transplant, give gentle low dose maintenance treatment to try to prevent relapse. Patients receive weekly low dose decitabine followed by venetoclax by mouth, starting by day 40 after transplant.

This phase 1 and 2 study plans 20 patients and measures safety and feasibility. At University Hospitals Cleveland and the Case Comprehensive Cancer Center, Benjamin Tomlinson leads it.

Public record; not medical advice.

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How these trials work: what Phase 1 actually is · common questions Not clinical evidence.