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Ultrasound Microbubble Cavitation (NCT07501650)

How Ultrasound Microbubble Cavitation worksNCT075016501 min

Ultrasound Microbubble Cavitation trial for Recurrent or Metastatic Head and Neck Cancer (NCT07501650). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with recurrent or metastatic head and neck cancer.

The idea: after each pembrolizumab infusion, give Definity, a microbubble agent by vein, and aim ultrasound at the tumor. The ultrasound makes the microbubbles cavitate, which may help pembrolizumab reach the tumor. Patients receive up to three cycles three weeks apart.

This phase 1 study plans 6 patients. At Thomas Jefferson University in Philadelphia, Joseph Curry leads it.

Public record; not medical advice.

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How these trials work: what Phase 1 actually is · common questions Not clinical evidence.