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Tazemetostat (NCT05627232)

How Tazemetostat worksNCT056272321 min

Tazemetostat trial for Relapsed or Refractory Acute Myeloid Leukemia (NCT05627232). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with acute myeloid leukemia that has come back or has not responded to prior treatment.

The idea: test two approaches with CPX-351, a liposomal chemotherapy given by vein. One part adds tazemetostat, a pill. The other pretreats with palbociclib before CPX-351. Both parts look for a safe dose to study further.

This phase 1 study plans 24 patients. At Thomas Jefferson University in Philadelphia, Gina Keiffer leads it.

Public record; not medical advice.

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How these trials work: what Phase 1 actually is · common questions Not clinical evidence.