TriangleSX-682 + Proton CSI (NCT07814352)
SX-682 + Proton CSI trial for Leptomeningeal Disease From Melanoma or NSCLC (NCT07814352). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with melanoma or non-small cell lung cancer that has spread to the lining of the brain and spinal cord, called leptomeningeal disease.
The idea: combine proton craniospinal irradiation, radiation to the whole brain and spine using protons, with SX-682, a pill taken twice a day. SX-682 is meant to help immune cells reach and attack the cancer.
The study looks at safety and whether the combination works.
This phase 1 study plans 40 patients. At Memorial Sloan Kettering Cancer Center in New York, Monica Chen leads it.
Public record; not medical advice.
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