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SBRT + atezolizumab and bevacizumab

SBRT With Atezo/Bev for HCC

  • RegistryNCT05488522
  • PhasePhase 1
  • StatusRecruiting
  • ConditionUnresectable Hepatocellular Carcinoma
  • SponsorAbramson Cancer Center at Penn Medicine
How SBRT + atezolizumab and bevacizumab works1 min

The drug

What is being tested.

Stereotactic Body Radiotherapy (SBRT) is a radiation procedure that delivers precise doses of radiation in fractions. See following section for more information on the schedule, dose, volume, and simulation of SBRT. Atezolizumab is an FDA-approved immune checkpoint inhibitor that is used in the treatment of advanced HCC.

The study

How the trial runs.

A phase I dose escalation and pharmacodynamic study of repeated dose stereotactic body radiotherapy (SBRT) administered with concurrent atezolizumab and bevacizumab for patients with advanced hepatocellular carcinoma (HCC)

Live record on ClinicalTrials.gov →

Eligibility

Who the study is looking for.

  • Subjects must have hepatocellular carcinoma (HCC) that is not amenable to curative-intent surgical or ablation (where surgery or ablation are not indicated due to disease extent, co-morbidities, or other technical reasons) and systemic therapy is indicated.

Inclusion criteria as written on the registry, trimmed. The full list, with exclusions, is on the live record.

For you, or someone you love

Whether or not this trial is the one, bring AI into your corner.

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  • Every record in one place

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  • Read in plain words

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  • Your people, in the loop

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Members also get a deeper analysis of their records and any sequencing data, including clinical trials that may fit, reviewed by a licensed physician before they receive it.

How these trials work: what Phase 1 actually is · common questions Not clinical evidence.

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