TrianglePRISM (NCT07139990)
PRISM trial for Extensive-Stage SCLC, Brain Metastases, Soft Tissue Sarcoma and Head and Neck Cancer (NCT07139990). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with several cancers, including extensive stage small cell lung cancer, brain metastases, soft tissue sarcoma and head and neck cancer.
The idea: personalize radiotherapy. Radiation is given as single high doses, called pulses, and later pulses are adapted to how each tumor responds on scans. Depending on the cohort, it is combined with chemoimmunotherapy or immunotherapy.
This phase 1 study plans 105 patients and looks at feasibility and safety. At UT Southwestern Medical Center in Dallas, Neil Desai leads it.
Public record; not medical advice.
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How these trials work: what Phase 1 actually is · common questions Not clinical evidence.