TrianglePralatrexate Conditioning (NCT07225985)
Pralatrexate Conditioning trial for Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma (NCT07225985). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with T cell non Hodgkin lymphoma that has come back or not responded to treatment, who are going to a donor stem cell transplant.
The idea: before the transplant, add pralatrexate, a drug given by vein that may block cancer cell growth, to bendamustine chemotherapy and total body irradiation. This prepares the body for the donor cells.
The study looks for side effects and the best dose of pralatrexate.
This phase 1 and 2 study plans 50 patients. At Fred Hutch in Seattle, Lorenzo Iovino leads it.
Public record; not medical advice.
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