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Pomalidomide after CAR T (NCT07532525)

How Pomalidomide worksNCT075325251 min

Pomalidomide after CAR T trial for Recurrent B Acute Lymphoblastic Leukemia (NCT07532525). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for CD19-positive B-cell leukemia or lymphoma that has returned or not responded, in patients who have already received an approved CAR T therapy.

The idea: help the CAR T cells last. To work best, the cells must expand and persist in the blood. Pomalidomide, a pill that stimulates the immune system, may improve that. Patients start it four to eight weeks after their infusion and take it for ten doses.

This is a small pilot, about 12 patients, and the first question is safety. At the University of Michigan in Ann Arbor, Jennifer Agrusa leads it.

Public record; not medical advice.

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