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Pembrolizumab + Image-Guided Surgery (NCT03760575)

How Pembrolizumab + Image-Guided Surgery worksNCT037605751 min

Pembrolizumab + Image-Guided Surgery trial for Malignant Pleural Mesothelioma (NCT03760575). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for malignant pleural mesothelioma, a cancer of the lining of the lungs, in adults.

The idea: add the immunotherapy drug pembrolizumab, given by vein before and after surgery, to standard care. Surgery uses indocyanine green image guidance to help remove the tumor, followed by the chemotherapy drugs cisplatin and pemetrexed.

This phase 1 study plans 20 patients and looks at safety, feasibility and early signs of benefit. At the University of Pennsylvania's Abramson Cancer Center, Corey Langer leads it.

Public record; not medical advice.

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How these trials work: what Phase 1 actually is · common questions Not clinical evidence.