TrianglePK-Directed Melphalan (NCT04483206)
PK-Directed Melphalan trial for Multiple Myeloma (NCT04483206). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with multiple myeloma who are having a stem cell transplant using their own cells.
The idea: personalize the dose of melphalan, the chemotherapy given before transplant. Patients get a first dose by vein, their blood levels are measured, and the second dose is set to reach a target exposure. Then their stem cells are infused.
This phase 1 study plans 90 patients and looks at the best dose and side effects. At Emory University's Winship Cancer Institute in Atlanta, Craig Hofmeister leads it.
Public record; not medical advice.
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How these trials work: what Phase 1 actually is · common questions Not clinical evidence.