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DB107-RRV (NCT06504381)

How DB107-RRV worksNCT065043811 min

DB107-RRV trial for High Grade Glioma (NCT06504381). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for newly diagnosed high grade glioma, a type of brain tumor, in adults 18 to 75.

The idea: add an experimental gene-based treatment to standard care. DB107-RRV is given into the brain during surgery and then by vein. DB107-FC is taken by mouth afterward, alongside radiation, with or without the chemotherapy temozolomide.

This phase 1 and 2 study first looks at safety and tolerability. At the University of California, San Francisco, Nicholas Butowski and Noriyuki Kasahara lead it.

Public record; not medical advice.

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How these trials work: what Phase 1 actually is · common questions Not clinical evidence.