TriangleCLAG-M/FLAG-Ida + TBI (NCT04375631)
CLAG-M/FLAG-Ida + TBI trial for Relapsed or Refractory AML, MDS or CMML (NCT04375631). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with acute myeloid leukemia, myelodysplastic syndrome, or chronic myelomonocytic leukemia that has come back or not responded to treatment, who are going to have a donor stem cell transplant.
The idea: before the transplant, give one of two chemotherapy combinations, called CLAG-M or FLAG-Ida, together with total body irradiation. The study raises the radiation dose in steps to find the best dose.
This phase 1 study plans 120 patients. At Fred Hutch and the University of Washington in Seattle, Filippo Milano leads it.
Public record; not medical advice.
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