TriangleRadiosurgery + Abemaciclib (NCT04923542)
Radiosurgery + Abemaciclib trial for HR+/HER2- Breast Cancer Brain Metastases (NCT04923542). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with hormone receptor positive, HER2 negative breast cancer that has spread to the brain.
The idea: combine stereotactic radiosurgery, a precise single session of brain radiation, with abemaciclib, a pill, plus standard endocrine therapy. Abemaciclib starts one week before radiation and continues after.
This phase 1 and 2 study plans 31 patients and measures how long brain tumors stay controlled. Kamran Ahmed and Heather Han of Moffitt Cancer Center lead it; it is currently enrolling at Ohio State.
Public record; not medical advice.
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