Venetoclax (NCT03214562)
Venetoclax trial for Acute Myeloid Leukemia (NCT03214562). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for acute myeloid leukemia, newly diagnosed or one that has come back.
The idea: add a targeted pill to standard intensive chemotherapy. The pill, venetoclax, blocks a protein called BCL-2. It is taken by mouth for part of each cycle, alongside a chemotherapy regimen called FLAG-IDA.
In a published report of 138 patients, 95 percent of newly diagnosed patients reached remission. Infections and low blood counts were common. It was a single group, with no comparison. At MD Anderson in Houston, Courtney DiNardo leads the study.
Public record; not medical advice.
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