TriangleSelinexor Maintenance (NCT07200102)
Selinexor Maintenance trial for Relapsed Multiple Myeloma After CAR T-Cell Therapy (NCT07200102). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for adults with multiple myeloma that came back after earlier treatment and who are getting CAR T cell therapy.
The idea: CAR T cells are a patient's own immune cells, reprogrammed to attack myeloma. There is no standard treatment to keep the cancer away afterward. This study adds selinexor, a pill that blocks a protein called XPO1, as maintenance after the CAR T infusion, for up to twelve cycles.
The study looks at safety and whether patients can stay on it.
This phase 1 study plans 20 patients. At Washington University School of Medicine in St. Louis, Mark Schroeder leads it.
Public record; not medical advice.
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