TriangleLNK001 (NCT07564232)
LNK001 trial for Advanced or Metastatic Clear Cell Renal Cell Carcinoma (NCT07564232). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for adults with advanced or metastatic clear cell kidney cancer.
The idea: LNK001 is a CAR T cell therapy: immune cells engineered to act only when they find two proteins on the cancer, ENPP3 and CAIX. After chemotherapy with cyclophosphamide and fludarabine by vein, the cells are given by infusion.
The study first looks for the recommended dose and safety, then whether that dose can help control the disease.
This phase 1 study plans 40 patients. At MD Anderson Cancer Center in Houston, Samer Srour leads it.
Public record; not medical advice.
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