TriangleFostamatinib (NCT06639724)
Fostamatinib trial for Pancreatic Ductal Adenocarcinoma (PDAC) (NCT06639724). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for resectable pancreatic cancer that has not spread, in adults.
The idea: add fostamatinib, a Syk kinase inhibitor currently FDA approved for ITP, to standard chemotherapy given before and after surgery. Patients take it by mouth twice a day for 7 days before chemotherapy, and then during chemotherapy. The main measure is whether surgery is delayed.
This phase 1b trial plans 36 patients. At the University of California, San Diego Moores Cancer Center, Andrew Lowy, listed as study chair, leads it.
Public record; not medical advice.
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