TriangleDC/AML Fusion Vaccine (NCT07374029)
DC/AML Fusion Vaccine trial for Acute Myeloid Leukemia (NCT07374029). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for acute myeloid leukemia, in patients treated with decitabine and venetoclax.
The idea: add personalized immune cells. A vaccine is made by fusing a patient's dendritic cells with their own leukemia cells. T cells stimulated by that fusion are collected, grown, and given back by vein.
This is the first time these primed T cells will be given to people. The study asks about feasibility and safety. At Beth Israel Deaconess in Boston, David Avigan leads it.
Public record; not medical advice.
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