TrianglePreemptive CIML NK Cell Therapy (NCT06138587)
Preemptive CIML NK Cell Therapy trial for Acute Myeloid Leukemia (NCT06138587). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for acute myeloid leukemia and related blood cancers that are at high risk of returning after a stem cell transplant.
The idea: a week after the transplant, give extra help against leftover disease. Natural killer cells from a related donor are exposed to signaling proteins called cytokines in the lab, which makes them memory-like. They are infused with five injections of interleukin-2.
The first question is safety and the best dose. At Dana-Farber in Boston, Roman Shapiro leads this early study.
Public record; not medical advice.
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