TriangleCD30-Armed T Cells (NCT05544968)
CD30-Armed T Cells trial for Relapsed or Refractory Hodgkin Lymphoma and CD30+ Lymphomas (NCT05544968). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for adults with Hodgkin lymphoma or other CD30 positive blood cancers that have come back or not responded to treatment.
The idea: collect the patient's own T cells, activate them, and coat them with a bispecific antibody that grabs CD30 on cancer cells and CD3 on the T cell. The armed T cells are then given back. This is the first time this treatment is tested in people.
The study looks at safety, feasibility, and how well it works.
This phase 1 study plans 42 patients. At the Medical College of Wisconsin in Milwaukee, Guru Subramanian Guru Murthy leads it.
Public record; not medical advice.
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