TriangleAcalabrutinib Maintenance (NCT05256641)
Acalabrutinib Maintenance trial for High-Risk Large B-Cell Lymphoma After Cellular Therapy (NCT05256641). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for adults with large B cell lymphoma at very high risk of coming back after cellular therapy, such as CAR T cells.
The idea: after cellular therapy, patients take acalabrutinib, a pill, as maintenance. Acalabrutinib is a small molecule inhibitor that may interfere with the ability of cancer cells to grow and spread.
The study looks at side effects and how well maintenance works.
This phase 1 and 2 study plans 24 patients. At UCLA's Jonsson Comprehensive Cancer Center in Los Angeles, Caspian Oliai leads it.
Public record; not medical advice.
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