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HEALTH PROFESSIONAL · SOURCE READING

Treatment of Unilateral Intraocular Retinoblastoma

Source: Retinoblastoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 3, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Intraocular Retinoblastoma

Treatment options for unilateral intraocular retinoblastoma include the following:

Enucleation for large intraocular tumors, with or without adjuvant chemotherapy based on pathology risk, when the eye cannot be saved.

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Conservative ocular salvage approaches when the eye and vision can be saved:

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Conservative ocular salvage approaches when the eye and vision can be saved:

Chemoreduction with either systemic or intra-arterial chemotherapy with or without intravitreal chemotherapy.

Conservative ocular salvage approaches when the eye and vision can be saved:

Local treatments, including cryotherapy, thermotherapy, and plaque radiation therapy.

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Preserved source evidence · Not medical advice