TREATMENT READING

Rectal Cancer

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66 sections · Source headings, not a ranked treatment list

Health professional · General Information About Rectal Cancer

Follow-Up After Treatment

Health professional · General Information About Rectal Cancer / Follow-Up After Treatment

Carcinoembryonic antigen (CEA)

Health professional

Treatment Option Overview for Rectal Cancer

Health professional · Treatment Option Overview for Rectal Cancer

Immunotherapy

Health professional · Treatment Option Overview for Rectal Cancer

Primary Surgical Therapy

Health professional · Treatment Option Overview for Rectal Cancer

Chemoradiation Therapy

Health professional · Treatment Option Overview for Rectal Cancer / Chemoradiation Therapy

Preoperative chemoradiation therapy

Health professional · Treatment Option Overview for Rectal Cancer / Chemoradiation Therapy

Postoperative chemoradiation therapy

Health professional · Treatment Option Overview for Rectal Cancer / Chemoradiation Therapy

Chemotherapy regimens

Health professional · Treatment Option Overview for Rectal Cancer / Chemoradiation Therapy / Chemotherapy regimens

Total neoadjuvant therapy

Health professional · Treatment Option Overview for Rectal Cancer / Chemoradiation Therapy

Treatment toxicity

Health professional · Treatment Option Overview for Rectal Cancer / Chemoradiation Therapy / Treatment toxicity

Long-course versus short-course radiation therapy

Health professional · Treatment Option Overview for Rectal Cancer / Chemoradiation Therapy

Capecitabine and fluorouracil dosing

Health professional

Treatment of Stage 0 Rectal Cancer

Health professional · Treatment of Stage 0 Rectal Cancer

Treatment Options for Stage 0 Rectal Cancer

Health professional · Treatment of Stage 0 Rectal Cancer / Treatment Options for Stage 0 Rectal Cancer

Polypectomy or surgery

Health professional

Treatment of Stage I Rectal Cancer

Health professional · Treatment of Stage I Rectal Cancer

Treatment Options for Stage I Rectal Cancer

Health professional · Treatment of Stage I Rectal Cancer / Treatment Options for Stage I Rectal Cancer

Surgery with or without chemoradiation therapy

Health professional

Treatment of Stages II and III Rectal Cancer

Health professional · Treatment of Stages II and III Rectal Cancer

Treatment Options for Stages II and III Rectal Cancer

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer

Preoperative chemoradiation therapy

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer

Neoadjuvant chemotherapy with FOLFOX without preoperative chemoradiation therapy (for select patients with lower-risk disease)

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer

Short-course preoperative radiation therapy followed by surgery and chemotherapy

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer

Postoperative chemoradiation therapy

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer

Surgery

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer

Primary chemoradiation therapy followed by intensive surveillance for complete clinical responders

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer

Immunotherapy

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer

Chemotherapy regimens

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer / Chemotherapy regimens

Preoperative oxaliplatin with chemoradiation therapy

Health professional · Treatment of Stages II and III Rectal Cancer / Treatment Options for Stages II and III Rectal Cancer / Chemotherapy regimens

Postoperative oxaliplatin-containing regimens

Health professional

Treatment of Stage IV and Recurrent Rectal Cancer

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer

Treatment Options for Stage IV and Recurrent Rectal Cancer

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer

Surgery with or without chemotherapy or radiation therapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer

Systemic therapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

5-FU

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Irinotecan and oxaliplatin

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Capecitabine

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Bevacizumab

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

FOLFOXIRI

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Cetuximab

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Ziv-aflibercept

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Ramucirumab

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Panitumumab

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Anti-EGFR antibody versus anti-VEGF antibody with first-line chemotherapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Regorafenib

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Fruquintinib

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Trifluridine-tipiracil

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Encorafenib with cetuximab for patients with BRAF V600E variants

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Systemic therapy

Sotorasib with panitumumab for patients with KRAS G12C variants

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer

Second-line chemotherapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer

Immunotherapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Immunotherapy

First-line immunotherapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Immunotherapy / First-line immunotherapy

Pembrolizumab monotherapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Immunotherapy / First-line immunotherapy

Nivolumab and ipilimumab

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Immunotherapy

Second-line immunotherapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Immunotherapy / Second-line immunotherapy

Pembrolizumab monotherapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Immunotherapy / Second-line immunotherapy

Nivolumab monotherapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer / Immunotherapy / Second-line immunotherapy

Nivolumab and ipilimumab

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment Options for Stage IV and Recurrent Rectal Cancer

Palliative therapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer

Treatment of Liver Metastasis

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment of Liver Metastasis

Surgery

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment of Liver Metastasis

Neoadjuvant chemotherapy for unresectable liver metastases

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment of Liver Metastasis

Local ablation for unresectable liver metastases

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment of Liver Metastasis

Adjuvant chemotherapy

Health professional · Treatment of Stage IV and Recurrent Rectal Cancer / Treatment of Liver Metastasis

Intra-arterial chemotherapy after liver resection

Preserved source evidence · Independent clinical review pending · Not medical advice