Skip to content
← Prostate Cancer

HEALTH PROFESSIONAL · SOURCE READING

Bilateral orchiectomy

Source: Prostate Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 14, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment Option Overview for Prostate Cancer / Hormonal Therapy and Its Complications

Benefits of bilateral orchiectomy include:[42]

Source links and citations

Ease of the procedure.

Compliance.

Immediacy in lowering testosterone levels.

Low cost relative to the other forms of ADT.

Disadvantages of bilateral orchiectomy include:[42,102]

Source links and citations

Psychological effects.

Loss of libido.

Less reversible impotence.

Hot flashes.

Osteoporosis.[102]

Source links and citations

Bilateral orchiectomy has also been associated with an elevated risk of coronary heart disease and myocardial infarction.[103-106]

Source links and citations

For more information, see Hot Flashes and Night Sweats.

Source links and citations

Publication references

Read the original reference and check its publication notices.

Preserved source evidence · Not medical advice