Skip to content
Triangle logo TriangleGet started
← Prostate Cancer

HEALTH PROFESSIONAL · SOURCE READING

Nonsteroidal antiandrogen monotherapy versus surgical or medical castration

Source: Prostate Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 14, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Recurrent Hormone-Sensitive or Hormone-Resistant Prostate Cancer / Hormonal Therapy for Recurring Disease

A systematic evidence review compared nonsteroidal antiandrogen monotherapy with surgical or medical castration from 11 randomized trials in 3,060 men with locally advanced, metastatic, or recurrent disease after local therapy.[21] The use of nonsteroidal antiandrogens as monotherapy decreased OS and increased the rate of clinical progression and treatment failure.[21][Level of evidence A1]

Source links and citations

Publication references

Read the original reference and check its publication notices.

Preserved source evidence · Not medical advice