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← Prostate Cancer

HEALTH PROFESSIONAL · SOURCE READING

Treatment Options for Stage IV Prostate Cancer

Source: Prostate Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 14, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Stage IV Prostate Cancer

Treatment options for patients with stage IV prostate cancer include:

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Hormonal manipulations.

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Hormonal manipulations with chemotherapy.

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Bisphosphonates.

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External-beam radiation therapy (EBRT) with or without hormonal therapy.

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Palliative radiation therapy.

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Palliative surgery with TURP.

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Watchful waiting or active surveillance/active monitoring.

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Radical prostatectomy with immediate orchiectomy (under clinical evaluation).

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Hormonal manipulations →Hormonal manipulations with chemotherapy →Bisphosphonates →External-beam radiation therapy (EBRT) with or without hormonal therapy →Palliative radiation therapy →Palliative surgery with transurethral resection of the prostate (TURP) →Watchful waiting or active surveillance/active monitoring →Radical prostatectomy with immediate orchiectomy →

Preserved source evidence · Not medical advice