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HEALTH PROFESSIONAL · SOURCE READING

Treatment Options for Recurrent Prostate Cancer

Source: Prostate Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 14, 2025 · Captured 2026-09-09.

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Context: Treatment of Recurrent Hormone-Sensitive or Hormone-Resistant Prostate Cancer

Treatment options for patients with recurrent prostate cancer include:

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Chemotherapy for hormone-sensitive or hormone-resistant prostate cancer.

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Immunotherapy.

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Radiopharmaceutical therapy.

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Radiopharmaceutical therapy.

Alpha emitter radiation therapy.

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Radiopharmaceutical therapy.

Beta emitter radiation therapy.

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Poly (ADP-ribose) polymerase (PARP) inhibitors for men with mCRPC and BRCA1, BRCA2, or ATM variants.

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Poly (ADP-ribose) polymerase (PARP) inhibitors for men with mCRPC and BRCA1, BRCA2, or ATM variants.

Olaparib.

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Hormone therapy with PARP inhibitors for men with mCRPC and BRCA1, BRCA2, or ATM variants.

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Hormone therapy with PARP inhibitors for men with mCRPC and BRCA1, BRCA2, or ATM variants.

PARP inhibitors as first-line therapy for men with mCRPC and BRCA1 or BRCA2 variants.

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Hormone therapy with PARP inhibitors for men with mCRPC and BRCA1, BRCA2, or ATM variants.

PARP inhibitors as first-line therapy for men with mCRPC and variants in homologous recombination repair genes.

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Preserved source evidence · Not medical advice