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Treatment Options for Amyloidosis Associated With Plasma Cell Neoplasms
Source: Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: April 25, 2025 · Captured 2026-09-09.
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Context: Treatment of Amyloidosis Associated With Plasma Cell Neoplasms
Treatment depends on assessing the extent of systemic damage from the amyloidosis and the underlying plasma cell dyscrasia.[1,2] A rising and elevated level of N-terminal pro-brain natriuretic peptide (NT-proBNP) may predict impending cardiac failure in cases of cardiac amyloidosis, and early treatment should be considered for these patients.[3]
Treatment options for amyloidosis associated with plasma cell neoplasms include:
Induction therapy.
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Stem cell rescue.
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Monoclonal antibody targeting of amyloid deposits (under clinical evaluation).
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