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← Myelodysplastic Syndromes

HEALTH PROFESSIONAL · SOURCE READING

Treatment of MDS

Source: Myelodysplastic Syndromes Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: September 19, 2024 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Therapies for myelodysplastic syndromes (MDS) are initiated in patients with a shorter predicted survival or in patients with clinically significant cytopenias. The impact of most MDS therapies on survival remains unproven.

Treatment options:

Supportive care.

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Disease-modifying agents.

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Disease-modifying agents.

Lenalidomide.

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Disease-modifying agents.

Immunosuppressive therapy.

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Disease-modifying agents.

DNA methyltransferase inhibitors.

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Disease-modifying agents.

Acute myeloid leukemia (AML) induction-type chemotherapy.

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Allogeneic hematopoietic stem cell transplant (HSCT).

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Preserved source evidence · Not medical advice