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← Langerhans Cell Histiocytosis

FOR PATIENTS · SOURCE READING

Treatment for Langerhans cell histiocytosis may cause side effects.

Source: Langerhans Cell Histiocytosis Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: June 6, 2024 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Context: Treatment Option Overview for LCH

To learn more about side effects that begin during treatment for cancer, visit Side Effects.

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Side effects from cancer treatment that begin after treatment and continue for months or years are called late effects. Late effects of cancer treatment may include the following:

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Slow growth and development.

Hormone imbalance.

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Hearing loss.

Bone, tooth, liver, and lung problems.

Changes in mood, feeling, behavior, learning, thinking, or memory.

Second cancers, such as leukemia, lymphoma, retinoblastoma, Ewing sarcoma, brain or liver cancer.

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Some late effects may be treated or controlled. It is important to talk with your child's doctors about the effects cancer treatment can have on your child. For more information, see Late Effects of Treatment for Childhood Cancer.

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Many patients with multisystem LCH have late effects caused by treatment or by the disease itself. These patients often have long-term health problems that affect their quality of life.

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Preserved source evidence · Independent clinical review pending · Not medical advice